Antimicrobial guanidine alkaloids

Honma, K., Tsuda, M., Mikami, Y, and Kobayashi, J. (1995) Aplysillamides A and B new antimicrobial guanidine alkaloids from the Okinawan marine sponge PsammaplysiUa purea. Tetrahedron, 51, 3745-3748. 

Marine organisms produce a wide range of alkaloids with potent bio activities, which include such specific classes as 3-aUcylpiperidine, guanidine, indole, polyamine, pyridoacridine, and pyrrole-imidazole alkaloids. Their biological activities vary from antimicrobial to neurological. 

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