Antihypertensive drugs INDEX

Labetalol is generally used effectively as an antihypertensive drug without reports of high vascular resistance, even in patients with pheochromocytoma. However, a case of pheochromocytoma with increased systemic vascular resistance and reduced cardiac index has been described (4). 

Because of their low therapeutic index and high potential for abuse, the barbiturates have largely been replaced by the safer benzodiazepines for sedative and hypnotic purposes. Nevertheless, they continue to be available for this purpose or in combination with other analgesic, antihypertensive, antiasthmatic, antispasmodic, or antidiuretic drugs. The combination of barbiturates, such as butalbital with analgesic preparations, is ironic. Not only do barbiturates lack analgesic properties, but at low doses they antagonize the... 

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