Plant steroids antifungal activity

Altemarla solani, removal of monosaccharide units of glycoalkaloids, 297,299 Ambrosia psllostachya. production of sesquiterpene lactones, 104 Antifungal activity, plant steroids, 286-301... 

Heterocycles are contained in a large number of agrochemicals . Triazoles, such as cyproconazole, are effective plant fnngicides and have mechanisms of action - inhibition of steroid synthesis - similar to those used medicinally. Other triazoles have limited antifungal activity, bnt are nseful plant-growth regulators, for example paclobutrazol. Another widely used fungicide is davicil. 

This article will review the antifungal activity of plant steroids but it should be noted that not all steroids act in an inhibitory capacity towards fungi. Certain sterols have a stimulatory effect on fungal development promoting growth, the differentiation of reproductive structures, and fertilisation in species of Pythium and Phytophthora which lack the ability to synthesize sterols (9). This subject is considered elsewhere in this volume. 

Antifungal activity has been demonstrated mainly in two groups of plant steroids, glycoalkaloids of the Solanum type and saponins. Members of both groups are comprised of a steroidal aglycone... 

---