Antidepressants in panic disorder

Lydiard RB, Ballenger JC. Antidepressants in panic disorder and agoraphobia. J Affect Disord 1987 13 153-168. 

Liebowitz MR. Antidepressants in panic disorders. Br J Psychiatry 1989 155[Suppl 6] 46-52. 

Newer antidepressants. Although the SSRIs are the only antidepressants formally approved for the treatment of panic disorder, recent evidence suggests that several other antidepressants are promising treatments for panic disorder as well. These include nefazodone, venlafaxine XR, mirtazapine, and reboxetine. Bupropion, however, does not seem to have apparent antipanic actions. Since the documentation of efficacy of these newer antidepressants in panic disorder is still emerging, they tend to be used as second-line therapy after SSRIs foil to improve panic or in patients who cannot tolerate them. 

When monitoring the effectiveness of antidepressants in panic disorder, it is important to allow an adequate amount of time (8 to 12 weeks) to achieve full therapeutic response. 

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See also in sourсe #XX -- [ , ]

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