Antibody-based strategies for tumour

1 Antibody-based strategies for tumour detection/destruction 

Clear identification of tumour-associated antigens would facilitate the production of monoclonal antibodies capable of selectively binding to tumour tissue. Such antibodies could be employed to detect and/or destroy the tumour cells. 

Upon administration, the anti-tumour 99mTc conjugate will congregate at the tumour site. The tumour can then be visualized using suitable y-ray detection equipment, such as a planar gamma camera. 

Anti-tumour monoclonal antibodies can also be used to deliver toxins to tumour sites. Toxins conjugated to therapeutic antibodies include ricin, pokeweed toxin, Pseudomonas toxin and 

Centrifugation, followed by filtration (0.2p) of antibody-containing fluid 

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