Antibodies combinatorial assembly

Barbas, C. F., Kang, A. S., Lemer, R. A, and Benkovic, S. J. (1991) Assembly of combinatorial antibody libraries on phage surfaces (Phabs)- the gene III site Proc Natl. Acad Sci USA 88, 7978-7982. 

Assembly of combinatorial antibody libraries on phages surfaces the gene III site. Proc. Natl. Acad. Sci. USA 88,7987-7982. 

Barbas CF III, Kang AS, Lemer RA, Benkovic SJ. Assembly of combinatorial antibody libraries on phage surfaces the gene III site. Proc. Natl Acad. Sci. U.S.A. 1991 88(18) 7978-7982. Barbas CF III, Burton DR, Scott JK, Silverman GJ, eds. Phage display of proteins and peptides A laboratory manual. 2001. Cold Spring Harbor Laboratory Press.Cold Spring Harbor, NY. Janda KD, Schloeder D, Benkovic SJ, Lemer RA. Induction of an antibody that catalyzes the hydrolysis of an amide bond. Science 1988 241(4870) 1188-1191. 

AS Kang, CF Barbas, KD Janda, SJ Benkovic, RA Lemer. Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces. Proc Natl Acad Sci USA 88 4363-4366, 1991. 

Highly diverse molecular libraries have become a vital tool in the search for molecules with novel properties. The antibody molecule in particular has been the focus of extensive development of different combinatorial strategies in order to obtain antibodies with novel specificities. These strategies include the re-assembly of naturally occuning genes encod-... 

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