Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Antibiotics halogenation reactions

Halogenation of a Cxe -macroUde. Reaction of the pyrrolidine enamine of the antibiotic leucomycin A3 (1) with NBS yields, after hydrolysis, the 17-bromo derivative (62%). A similar reaction is observed with NCS (66%, yield). In contrast, reaction with perchloryl fluoride in limited amounts results in fluorination at Ci, and Cm. The Cm-rnonofluoride was made indirectly by reaction first with NBS and then with perchloryl fluoride the bromofluoro... [Pg.270]

See other pages where Antibiotics halogenation reactions is mentioned: [Pg.38]    [Pg.315]    [Pg.215]    [Pg.127]    [Pg.110]    [Pg.234]    [Pg.42]    [Pg.472]    [Pg.106]    [Pg.315]    [Pg.31]    [Pg.283]    [Pg.225]    [Pg.110]    [Pg.1312]    [Pg.60]    [Pg.229]    [Pg.238]    [Pg.978]    [Pg.130]    [Pg.283]    [Pg.536]    [Pg.386]    [Pg.384]    [Pg.60]    [Pg.306]    [Pg.343]    [Pg.259]    [Pg.273]    [Pg.56]    [Pg.380]    [Pg.669]    [Pg.270]    [Pg.94]    [Pg.96]    [Pg.220]    [Pg.978]    [Pg.94]    [Pg.96]    [Pg.964]    [Pg.389]    [Pg.128]    [Pg.118]    [Pg.601]    [Pg.34]   
See also in sourсe #XX -- [ Pg.726 ]



SEARCH



Antibiotics reaction

Halogenation reactions

Reactions halogens

© 2024 chempedia.info