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It was demonstrated that the rate of aerobic phosphorylation in rat liver mitochondria is depressed by dicoumarol [274]. Antibacterial activity of dicoumarol has been suggested to be related to its uncoupling characteristic [10]. This compound was reported to be a powerful uncoupler of oxidative phosphoiylation, which inhibits phosphorylation at every step in the electron transport chain [275]. [Pg.375]

See also in sourсe #XX -- [ Pg.23 , Pg.354 , Pg.375 ]