Anti-HIV-1 activity of inophyllums

An inophyllum series was isolated from the Malaysia tree, Calophyllum inophyllum Linn (bioassay-guided procedure) (-l-)-inophyllum B (3), P (4), C (11), E (12), A (17), D (18), inophyllum G-1 (19), G-2 (20), calophyllic acid (28), and isocalophyl-lic acid (29). The (+)-inophyllum P (4), an enantiomer of soulattrolide (16) and as 

TABLE 8-3. Activities of Calanolides Against Viruses Resistant to HIV-l-Specific Inhibitors 

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