Anthrax Lethal Factor LF

The development of compact, field-deployable sensors is highly desirable for prompt, on-site detection of active Bacillus anthracis bacteria, which would eliminate the need to send samples for diagnosis to a remote laboratory As a first step toward this goal, we describe the development of an OLED-based 

In developing OLED-based oxygen and glucose sensors, oxygen-sensitive Ru, Pt, and Pd-based dyes, with large Stokes shifts ( 100nm), were used. However, the rhodamine-based dye has a Stokes shift of only 20nm. As 

---

In other instances, where analyte-sensitive dyes with a narrower Stokes shift are utilized, the contribution of the long-wavelength EL tail to the background can be large, reducing the detection sensitivity and deteriorating the LOD. An example for that behavior is that of a sensor for anthrax lethal factor (LF), which is one of the three proteins of the anthrax toxin secreted by the live Bacillus anthracis bacterium. The development of a compact, field-deployable, and low-cost sensor for prompt, on-site detection of... 

---