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Antagonist-bound state

The conservation equation for receptors defines the total number of receptors as the sum of bound and free receptors (Equation (6.3)). Although the receptor population is in fact made up of subpopulations of receptors in high- and low-affinity states, this is most relevant for modeling agonist interactions. Because most tracers are radiolabeled antagonists, this simplified model is sufficient for most tracer studies. The conservation and mass action equations (Equations (6.3) and (6.4)) can be rearranged to calculate the number of bound receptors ... [Pg.222]

See other pages where Antagonist-bound state is mentioned: [Pg.67]    [Pg.1861]    [Pg.599]    [Pg.164]    [Pg.68]    [Pg.67]    [Pg.1861]    [Pg.599]    [Pg.164]    [Pg.68]    [Pg.466]    [Pg.11]    [Pg.19]    [Pg.20]    [Pg.4]    [Pg.127]    [Pg.323]    [Pg.41]    [Pg.186]    [Pg.1856]    [Pg.1856]    [Pg.163]    [Pg.250]    [Pg.364]    [Pg.323]    [Pg.196]    [Pg.238]    [Pg.661]    [Pg.66]    [Pg.60]    [Pg.5]    [Pg.531]    [Pg.6]    [Pg.544]    [Pg.294]    [Pg.302]    [Pg.165]    [Pg.159]    [Pg.299]    [Pg.396]    [Pg.403]    [Pg.400]    [Pg.104]    [Pg.7]    [Pg.320]    [Pg.202]    [Pg.216]    [Pg.321]    [Pg.322]    [Pg.661]    [Pg.1336]    [Pg.3115]    [Pg.3116]   
See also in sourсe #XX -- [ Pg.67 ]



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Bound state

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