Annulation of Anilines and Related Compounds with Alkynes

5 ANNULATION OF ANILINES AND RELATED COMPOUNDS WITH ALKYNES 

A host of mechanistic studies have been performed [150], and it is widely believed that the reaction proceeds via six-membered palladacycles such as 72, formed from 

By definition, palladium- and copper-catalyzed aryl amidation, aryl etherification, and aryl thioetherification reactions are transformations designed to construct bonds between heteroatoms and aromatic rings. Thus, it is perhaps not surprising that these 

Jensen, H. Pedersen, B. Bang-Andersen, R. Madsen, M. Jorgensen, Angew. Chem. Int. Ed. 2008, 47, 888. 

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