Annulating synthons for highly

Thio-l, 2-0-Isopropylidene Acetals Annulating Synthons for Highly Hydroxylated... 

Analogues of complex saccharides, in which one or other of the acetal oxygens is replaced by a methylene residue or other heteroatoms, have received attention as biochemical probes and as potential therapeutic agents. The use of l-thio-1,2-isopropylidene acetals (TIA s) as annulating synthons for highly hydroxylated systems is illustrated by the synthesis of (3-C-, p-aza-C- and P-carba- galacto disaccharides. 

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