4-Anilino-3-trimethylsilyl

An intramolecular cyclization of iV-anilino- and iV-benzyl-substituted propargyl trimethylsilyl ethers with Lewis acid catalysis provides the quinolines and isoquinolines, respectively <20040L2361>. An intramolecular aza-Diels-Alder reaction has been used as a key step in the synthesis of luotonin (Scheme 69) <20040L4913>. An analogous reaction afforded the dihydroquinoline as a single diastereomer (Equation 132) <2000TL5715>. 

N-Trimethylsilyl-anilino)-thioxo-methanphos-phonstiure-bis-[diethylamid 87%... 

Phosphorsaure-anilid-bis-[N-alkyl-anilide] sind aus Pliosphorsaure-anilid-dichlo-rid und N-Alkyl-anilino-magnesiumjodid in Diethylether (30-40%)924 erhaltlich. Wenig reaktive Amine werden als N-Trimethylsilyl-Derivate in siedendem Benzol umgesetzt925 z.B. ... 

The proton spectra of 1-substituted 3-nitropyrazoles [296], 5-substituted 3-methyl-l-aryl-4-nitropyrazoles [297, 298], 1,3- and l,5-diphenyl-4-nitropyra-zoles [281], 5-iodo-4-nitro-l,3-dimethylpyrazole [299], l-methyl-3-nitro-4- and l,3-methyl-4-nitro-5-phenylethynylpyrazoles [300], l-methyl-3-nitro-5-methoxy-carbonylpyrazole [301], l-methyl-3-nitro- and l-methyl-5-nitro-4-cyanopyrazoles [302], A-(2,4-dinitrophenyl)nitropyrazoles [303], a- and [3-anomers of 3-nitro-and4-nitropyrazolyl-l-ribonucleosides [304, 305], 3-substituted 1,5-dimethyl- [306] and 5-substituted l,3-dimethyl-4-nitropyrazoles [279], l-acetyl-3-anilino-4-nitro-5-dimethylaminopyrazoles [307], 3-substituted 4-nitro-5-carboxylic acid derivatives [308, 309], 4-nitropyrazolo[4,3-e][l, 4]diazepin-5,8-diones showing antimicrobial activity [310], l-heteryl-4-nitropyrazole derivatives [311], 3-nitro- and 5-nitro-l-methylpyrazole [312], 4-nitro-5-(trimethylsilyl)pyrazole [313], 3-methyl-4-nitro-pyrazol-5-ones [298], and some other nitropyrazoles [248, 314-320] have been examined. 

Propan 2-(N-Methyl-anilino)-l-trimethylsilyl- E16d, 782 (Hydro-ami nierung)... 

Di-tcrt.-butyl-3-(N-trimethylsilyl-anilino-thiocarbonylphosphan-ylidene)- 3016... 

An extension of these methods that employs hydrazoic acid as an azide donating agent was developed by Tsuge and co-workers. They used TMSA (146) and allowed it to react with synunetrical M,hf -diphenylcarbodiimide or Nd f -dialkyl carbodiimides 239 in dry benzene at 50-60 °C for 48 hours. The products of these conversions were l-phenyl-5-[N-(trimethylsilyl)-anilino]-... 

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