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Anhydro vinblastine

The allylic alcohol (273) has also been used in a preparation of 15-oxo-15,20S-dihydrocatharanthine (275a), required for partial synthesis of anhydro-vinblastine (q.v.).125 Oxidation of (273) could be achieved by a variety of oxidizing agents, of which triphenylbismuth carbonate appeared to be the best (Scheme 39). Oxidation of the allylic alcohol group was followed by Michael addition of Nb to the... [Pg.232]

C. roseus cell suspension cultures (94), thus administration of [21 a-3H] anhydro-VLB to a cell-free homogenate of suspension culture cells c. roseus afforded radioactive [3h]-vinblastine (94). [Pg.638]

See other pages where Anhydro vinblastine is mentioned: [Pg.249]    [Pg.225]    [Pg.4165]    [Pg.249]    [Pg.225]    [Pg.4165]    [Pg.406]    [Pg.356]    [Pg.262]   
See also in sourсe #XX -- [ Pg.301 , Pg.314 , Pg.319 ]



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