CXC chemokines angiostatic

Angiostatic CXC Chemokines Attenuate Angiogenesis Associated with Tumorigenesis... 

Table 1 CXC chemokines with angiogenic and angiostatic activities including their receptors that bind the angiogenic and angiostatic CXC chemokines...

Putative Endothelial Cell CXC Chemokine Receptors that Bind Angiogenic and Angiostatic CXC Chemokines... 

Fig. 2. The role of CXC chemokines in regulating angiogenesis in the context of tumori-genesis. The over- and underexpression of the angiogenic (ELR+ CXC chemokines) and angiostatic (ELR CXC chemokines), respectively, lead to tumor progression via the promotion of tumor-associated neovascularization. In contrast, attenuation of the angiogenic or reconstitution of the angiostatic CXC chemokines leads to tumor regression via the inhibition of tumor-associated neovascularization.

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