Androgen adrenal, suppressing secretion

Patients with CAH require lifelong glucocorticoid replacement therapy to correct the deficiency in cortisol secretion. This in turn suppresses ACTH production, excess adrenal 17-hydryoxyprogesterone,and excess androgen production. Hydrocortisone is the cortico-... 

In adrenogenital syndrome and adrenal virilism, an attempt may be made to suppress excess adrenal androgen secretion by inhibiting pituitary corticotropin production by means of prednisolone or dexamethasone. Suppression of androgen production is effective if there is adrenal hyperplasia, but not if an adrenal tumour is present. Hairiness, which women especially dislike in themselves, is often unaffected even though good suppression is achieved, and menstruation recommences. 

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