Anamirta cocculus Picrotoxin

Picrotoxin is a mixture of pircotin (non-toxic) and picrotoxinin, which occurs in the seeds of the Asiatic climber Anamirta cocculus (levent berry, cockles). It is a non-competitive antagonist at the y -aminobutyric acidA (GABAa) receptor. 

Picrotoxin, a component of Anamirta cocculus and A. paniculata, was first used as a... 

Cocculus. Fish-barry Indian bsrry Gaecufus indi-cus oriental berry. Dried fruit of Anamirta cocculus (L.) Wight Am.. Menispermaceae. Habit. East Indies, Malay Archipelago. Consiir. Menispermine, paramenispermine, about 1% picrotoxin, picrotoxic acid, cocculine alkaloid, about 50% fat. Poisonous/... 

Picrotoxin, Cocculin. CwHmO mol wt 602.57. C 59.79%, H 5.69%, O 34.52%. Bitter principle isolated from the seed of Anamirta cocculus L. Wight Arn., Meni-spermaceae. also found in Tinomiscium philippinense Diels. Extraction procedure dark, J. Am diem. Soc. 57, 1111 (1935). For a complete chemical bibliography up to April 1949 see Helv Chim Acta 32, 1859 (1949). Picrotoxin is a molecular compd of one mole picrotoxinin, q.v.. and one mole picrotin, q. V-, into which it is readily separated. Crystal and molecular structure L. Dupont er al. Acta Crystallogr. B32, 2987 (1976). 

Picrotoxin (= mixture of Anamirta paniculata (= A. cocculus GABAA-R antagonist (0.2) ... 

Cocculus indicus The berry of a woody vine (Anamirta coceulousi of the Cast indies. It Is very poisonous and yields Picrotoxin. 

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