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Analysis of active pharmaceutical

V. ANALYSIS OF ACTIVE PHARMACEUTICAL INGREDIENTS AND DRUG PRODUCTS... [Pg.1]

In Structural analysis of active pharmaceutical ingredients, crystal polymorphism is an important subject of study. Crystal structures are determined by X-ray diffraction studies. Once the correlation between crystal polymorphs and their infrared spectra has been established, it can then become a relatively easy task to distinguish polymorphs by measuring their microphotographs and corresponding microscopic infrared spectra, as infrared microspectrometric measurements can be conveniently performed within a much shorter time than X-diffraction analysis. [Pg.233]


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