Ammonium salicylate sulphate

H. Stamm also measured the solubilities of the salts of the alkalies in liquid ammonia —potassium hydroxide, nitrate, sulphate, chromate, oxalate, perchlorate, persulphate, chloride, bromide, iodide, carbonate, and chlorate rubidium chloride, bromide, and sulphate esesium chloride, iodide, carbonate, and sulphate lithium chloride and sulphate sodium phosphate, phosphite, hypophosphite, fluoride, chloride, iodide, bromate, perchlorate, periodate, hyponitrire, nitrite, nitrate, azide, dithionate, chromate, carbonate, oxalate, benzoate, phtnalate, isophthalate ammonium, chloride, chlorate, bromide, iodide, perchlorate, sulphate, sulphite, chromate, molybdate, nitrate, dithionate, thiosulphate, persulphate, thiocyanate, phosphate, phosphite, hypophosphite, arsenate, arsenite, amidosulphonate, ferrocyanide, carbonate, benzoate, methionate, phenylacetate, picrate, salicylate, phenylpropionate, benzoldisulphonate, benzolsulphonate, phthalate, trimesmate, mellitate, aliphatic dicarboxylates, tartrate, fumarate, and maleinate and phenol. 

Other method was described by Wagner (1+6) for the analysis and detection of salicylic acid and derivatives including salicylamide. Development was effected by using color reactions, with ferric ammonium sulphate, ammoniacal silver nitrate solution, potassium nitrate, HC1 and 5% KOH through diazotization and coupling with, 2-naphthol and coupling with diazotized sulphanilic acid. 

More recent investigators contend that salicylic acid can only be mercurated to give pure products when mercuric sulphate is used. A mixture of the anhydrides of o- and p hydroxymercuri-salicylic acids is formed, the latter 3delding p-thiocyanomercuri-salicylic acid with potassium or ammonium thiocyanates, and sodium p-sodium sulphitomercuri-salicylate with sodium sulphite. 

Dissolve 1 g of salicylic acid in 60 ml of ethanol, adjust the volume to 100 ml with water dilute 10 ml of this solution to 1 litre as a standard, making 1 ml = 0-1 mg of acid. Dissolve 0-6 g of aspirin in a measuring cylinder in 9 ml of ethanol and dilute with water to 90 ml. Take two similar Nessler cylinders into one pour 60 ml of the solution, into the other the remaining 30 ml with 3 ml of ethanol and adjust to the volume of the first. There is thus a difference of 200 mg in the amount of aspirin in the two solutions. Add 1 ml of 1 per cent acid ferric ammonium sulphate solution to each, mix and match the colour by adding the standard salicylic acid solution from a burette. Each ml of standard is equivalent to 0-05 per cent of salicylic acid in the sample. 

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