5-Aminoorotic acid

Aminoorotic acid, a 160 1-Aminopentane, p53 4-Aminophenyl phenyl ether, p70 Aminophenyl sulfones, d36, d37... 

Aminoorotic acid, A-00290 yV-(/ -Aminophenyl)glycine, A-00323 5 -Amino-2, 3,3, 4-tetrahydro-4,4,6-... 

Pyrimido[5.4-r/]pyrimidines 5 and 6 are readily prepared by the condensation of 5-amino-2,6-dihydroxypyrimidine-4-carboxylic acid ( orotic acid ) with formamidc or urea. Reaction of the starting pyrimidine with formamide gives pyrimido[5,4-c/]pyrimidine-2,4,8-triol (5), which can also be prepared from ethyl 5-aminoorotate in 72% yield. In this case, the 5-amino group is first converted into the (ethoxymethylene)amino derivative and then treated with ammonia.207 The corresponding tetrol 6 results from reaction of the starting pyrimidine with urea.152,203... 

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