Aminoketones, from

V 0 I Q H T a-Amlnokelone synthesis Synthesis ol o-aminoketones from a-hydroxykeiones. 

Transformations on this support included the synthesis of aminoketones from supported chloroketones as weU as biarylaldehydes after Suzuki cross-couphng reactions of supported bromo-benzaldehydes [21]. This dendritic polyglycerol was... 

Upon reaction with amino acids, in the Strecker degradation, unstable imines are formed, which may easily decarboxylate, leaving an enamine, which upon hydrolysis yields an aldehyde from the amino acid and an a-aminoketone from the di-carbonyl-compound. 

Another way to form a-aminoketones from a-amino acids is via the Dakin-West reaction, in which amino acids are treated with aliphatic acid anhydrides to give ketone amides. Thus, reaction of ( )-phenylalanine with the appropriate aliphatic acid anhydrides followed by acidic hydrolysis afforded keto-amide 1271. Cyclization of 1272 with potassium cyanate gave 5-alkyl-4-benzyl-l,3-dihydroimidazol-2-ones 1273 (Scheme 322) <2002JHC375>. 

V O I G H T a-Aminoketone Synthesis Synthesis of a-aminoketones from a-hydroxyketones (see 1st edition). 

Aminoketones from ketones COCH COCH-CH2N<... 

Potassium carbonate/piperidine y -Aminoketones from 2-acetylenealcohols... 

Formic acid Cyclic a-aminoketones from cyclic tert. 2-iminoalcohols with ring expansion s. 18, 781 HCOOH Q... 

Aminoketones from 2,3,4,5-tetrahydropyrimidine ring and reverse reaction Exchange of 2-substituents of 2,3,4,5-tetrahydropyrimidines... 

Sodiumjliq, ammonia tert-butanol ) -Aminoketones from isoxazoles s. 28, 204... 

Magnesium methyl carbonate -Aminoketones from azomethines... 

M ethoxy magnesium methyl carbonate / -Aminoketones from azomethines s. 25, 620 s. a. Synthesis 1974, 284... 

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