Amino sequence alignments, algorithms

Figure 4 Sequence alignment of the deduced amino acid sequence of P. putida PepA with the primary sequences of E. coli aminopeptidase A, Rickettsia prowazekii aminopeptidase A, and bovine eye lens leucine aminopeptidase (blLAP). The bottom line is the consensus sequence, which was generated by the multiple sequence alignment algorithm Clustal W. Residues in boldface and marked with an arrow represent residues of the blLAP that have been shown to be involved in metal coordination and/or inhibitor binding.

Figure 2. Alignment of the human mitochondrial ceramidase to homologous ceramidases from various organisms. Sequences of ceramidases were aligned using ClustalW algorithm of the Mac Vector program. Amino acids identical are shaded in grey and consensus residues are shown under the alignment. Amino acids of the same group are shaded in white.

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