Amino adds electrostatic charges

The powerful tool of molecular genetics allows the modification of each single amino add in the peptide chain of a protein, e.g. ddetion of side residues necessary for isoprenylation or palmitoylation1361 or introduction of additional charged amino acids for electrostatic interaction with the plasma membrane.1371 Even some artificial modifications can be introduced by means of recombinant enzymes as shown above. 

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