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Amino acids difluoromethylene

Ema, T, Kadoya, T, Akihara, K., and Sakai, T. (2010) Chemoenzymatic synthesis of optically active alcohol and p-amino-acid derivative containing the difluoromethylene group. J. Mol. Catal. B Enzym., 66 (1-2), 198-202. [Pg.109]

One fluorine atom is leaving as a fluoride ion, and the exocylic double bond to the difluoromethylene group is attacked by a hydroxide anion. Elimination of hydrogen fluoride gives an acyl fluoride that is readily hydrolyzed to the final product, 2-amino-4-trifluoromethylbenzoic acid (K) [59],... [Pg.68]


See other pages where Amino acids difluoromethylene is mentioned: [Pg.118]    [Pg.118]    [Pg.1436]    [Pg.1436]    [Pg.234]    [Pg.118]    [Pg.33]    [Pg.207]    [Pg.221]    [Pg.222]    [Pg.328]    [Pg.325]    [Pg.247]   
See also in sourсe #XX -- [ Pg.169 ]




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Difluoromethylene

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