Amino Acid Sequence of the Isoforms

Hasegawa et al. (1992) sequenced LClTa and LClTb of porcine aorta myosin (Fig. 9), both containing 150 amino acid residues with acetylated N-terminal cysteines. Only the C-terminal region differs between the 

TABLE I Distribution of LCl7 Isoforms in Smooth Muscles 

Nabeshima et al. (1987) have isolated two cDNA clones for LC17 mRNA from chicken gizzard and fibroblast cDNA libraries. Sequence analysis of the two 

The physiological role of LC17 isoforms has been studied by several investigators. The actin-activated MgATPase activity of phosphorylated and non-phosphorylated myosin from porcine gastric corpus (0% LClTb, Table I) was twofold higher that that of myosin from porcine aorta (43% LClTb) (Helper et al., 

LC17a or skeletal LCl or LC3 isoforms, also suggest that the velocity in the in vitro motility assay is determined by HC and not by the isoform of ELC (Tiybus, 1994). 

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