Amines ethoxy acetylene

The starting Fischer-type carbene complexes 1 were obtained by Michael addition of dimethylamine to the carbon-carbon triple bond of the corresponding ethoxy-(phenylethynyl)carbenes. In this regard, de Meijere and co-workers observed that the reactions of several primary and secondary amines with this sort of carbenes, in particular chromium derivatives 3 containing bulky substituents at the terminal carbon of the acetylenic unit, result in formation of the aminoallenylidene derivatives 5 as by-products of the expected Michael adducts 4 (Scheme 2) [20-24]. 

Dehydrative Condensation of Carboxylic Acids with Amines and Alcohols. For reversible fluorescent labeling of amino groups, ethoxy(trimethylsilyl)acetylene was used as a dehydrating reagent to couple dansylaminomethylmaleic acid (DAM) with benzylamine through a maleic anhydride intermediate (eq 6). ... 

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