Amido stannane

These are polar reactions with the components polarised in the sense Sn0+-N° and M6+-X°. Different behaviour is observed in the reaction of the aminostannanes with tin hydrides in which the polarisation appears to be in the sense Sn5-H5+ (equation 16-40), and the products are the distannane and amine. These hydrostannolysis reactions of amino- and amido-stannanes provide an important route to Sn-Sn bonded compounds, and are discussed in Section 18.2.1.3. 

Reincorporation of the tin can be avoided by using a tri wry/stannane precursor.156 This means that the product organolithium can be trapped with other electrophiles, provided that the solvent is 10 1 hexane-ether, and not THF, which otherwise protonates the product organolithium.157 The hexane-ether mixture slows down the tin-lithium exchange reaction dramatically, and it proceeds only at room temperature. Cyclisation of 323 thus leads to the synthesis of a simple GABA uptake inhibitor 324. A-acyl pyrrolidines cannot be made directly from a-amido organolithiums, as these fail to cyclise, possibly because they are too well stabilised by O-Li coordination.138... 

Sieh D, Burger P. Formation of a stannyl amido complex by the reaction of a terminal iridium nitrido complex with a stannane. Z Anorg Allg Chem. 2015 641 52-55. Gloaguen Y, Rebreyend C, Lutz M, et al. An isolated nitridyl radical-bridged Rh(N-) Rh complex. Angew Chem Int Ed. 2014 53 6814-6818. 

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