Amido-Grignard

Use of Amido Grignard Reagents in Inorganic Chemistry—Synthesis and Crystal Structure of Anti (Ragaini et al., 1997)... 

Imidazolium ligands, in Rh complexes, 7, 126 Imidazolium salts iridium binding, 7, 349 in silver(I) carbene synthesis, 2, 206 Imidazol-2-ylidene carbenes, with tungsten carbonyls, 5, 678 (Imidazol-2-ylidene)gold(I) complexes, preparation, 2, 289 Imidazopyridine, in trinuclear Ru and Os clusters, 6, 727 Imidazo[l,2-a]-pyridines, iodo-substituted, in Grignard reagent preparation, 9, 37—38 Imido alkyl complexes, with tantalum, 5, 118—120 Imido-amido half-sandwich compounds, with tantalum, 5,183 /13-Imido clusters, with trinuclear Ru clusters, 6, 733 Imido complexes with bis-Gp Ti, 4, 579 with monoalkyl Ti(IV), 4, 336 with mono-Gp Ti(IV), 4, 419 with Ru half-sandwiches, 6, 519—520 with tantalum, 5, 110 with titanium(IV) dialkyls, 4, 352 with titanocenes, 4, 566 with tungsten... 

Perfluoroalkyl- and perfluoroaryltitanium compounds were prepared m situ via reaction of the corresponding Grignard reagents with chlorotris(diethyl-amido)titaniuin [2SS] Reaction of the titanium compounds with aldehydes resulted in fluoroalkylative amination [2SS] (equation 192)... 

Schultz and Harrington [37] added Grignards to a-amido enone (see Table 4, entry 6). They obtained high diasteromeric excesses with a variety of nucleophiles for example, with methyl Grignard reagent, the d.e. ranged from 85 to 90%. 

These 0x0 Re complexes can furnish various derivatives, for example, with N-, 0-, S-, or C- ligands, that is, Re oxo-amido, -imido, -alkoxide, -phenoxide, -diolate, -thiolate, -alkyl, or - aryl complexes, on reactions of (13) or (14) with amines, alcohols, phenoxides, diols, thiols, organozinc, or Grignard reagents, respectively. 

Reduction of an alkylmercury halide or acetate with a borohydride provides an alternative method for accessing a carbon radical species (see Scheme 4.11). The alkylmercury compound can be prepared by one of a number of methods, such as from the corresponding Grignard reagent or from addition of Hg(OAc)2 to an alkene. For example, intramolecular amido-mercurafion of the alkene 50, followed by formation of the alkyl radical and addition to methyl acrylate provides a route to the alkaloid 8-coniceine (4.46). ... 

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