Amides bridged azabicyclic systems

Reaction of propargyltrimethylsilane with oj-ethoxylactams under the influence of boron trifluoride affords (u-allenyllactams. The intramolecular version of this process gives rise to bridged azabicyclic systems containing the uncommon a-allenic amide functionality (equation 8). ... 

The intramolecular acid-catalyzed reacdon of 2-propargylsilanes of structural type (117) with N-acy-liumion ion precursors leads to bridged azabicyclic ring systems (118 Scheme 33) which contain an a-allenic amide fimcdon. These bicyclic products serve as intermediates to highly funcdonalized trans-fused ring systems possessing a 1,3-diene moiety. 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ ]

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