Amaryl

Glimepiride (Y) Amaryl Short-acting insulin secretagogues 1,2,4 1-2 0.5-1 2 8 24 hours Metabolized in liver to inactive metabolites... 

Gllmepirlde (Amaryl) Second generation Tablets 1, 2, 4 mg sulfonylurea Hypoglycemic... 

Glimepiride (Amaryl) is metabolized to at least one active metabolite. It is quickly absorbed from the gastrointestinal tract within an hour of oral administration and excreted in the urine and feces. Its half-life varies from 5 to 9 hours depending on the frequency of multiple dosing. 

Amaryl (Glimepiride) 6.9 (0.3) 7.2 (0.3) 5.8 (0.2) A second-generation sulfonylurea. Blocks ATP-sensitive K-channels in the membrane of beta cells, stimulating the release of insuhn. 

Galantamine HBr was marketed under the brand name Remi-nyl. The name was changed in 2005 to Razadyne to avoid confusion with the diabetes drug Amaryl (glimeperide). 

Exenatide (Byetta) Glimepiride (Amaryl) Glimepiride/Pioglitazone (Duetact)... 

The sulfonylureas stimulate insulin secretion by pancreatic cells. As an old class of diabetes drug, the sulfonylureas have been improved steadily over the years. The original sulfonylurea is tolbutamide (A.66) (Figure A.21). Later and more potent sulfonylureas include glipizide (Glucotrol, A.67), glyburide (A.68), and finally glimepiride (Amaryl, A.69). 

Product Monograph Amaryl, Sanofi-Aventis Canada Inc. http //www.sanofi-aventis. ca/products/en/amaryl.pdf (September 10, 2009). 

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