MAOIs Amantadine

Dicyclomine (Bentyl) [Anrimuscarinic, GI Anrispasmodic/ Anticholinergic] Uses Functional IBS Action Smooth-muscle relaxant Dose Adults. 20 mg PO qid T to 160 mg/d max or 20 mg EM q6h, 80 mg/d - qid then T to 160 mg/d, max 2 wk Feds. Infants >6 mo 5mg/dose tid-qid Children 10 mg/dose tid-qid Caution [B, -] Contra Infants <6 mo, NAG, MyG, severe UC, BOO Disp Caps, tabs, syrup, inj SE Anticholinergic SEs may limit dose Interactions T Anticholinergic effects W/ anticholinergics, antihistamines, amantadine, MAOIs, TCAs, phenothiazides T effects OF atenolol, digoxin X effects H7 antacids X effects OF haloperidol, ketoconazole, levodopa, phenothiazines EMS Avoid procainamide usage, may T adverse effects may T effects of digoxin, monitor... 

DA agonists levodopa, bromocriptine, 1 pergolide, pramipexole 1 MAO-B inhibitor selegOine 1 AAAD inhibitor carbidopa I M blockers benztropine, trihexiphenidyl j COMT inhibitor tolcapone 1 Amantadine MAOIs phenelzine, tranylcypromine TCAs amitriptyline, imipramine, clomipramine SSRIs fluoxetine, paroxetine, sertraline Others bupropion, mirtazapine, trazodone, venlafaxine... 

Hyoscyamine (Anaspaz, Cystospaz, Levsin, Others) [Antispasmodic/Anticholinergic] Uses Spasm w/ GI bladder disorders Action Anticholinergic Dose Adults. 0.125-0.25 mg (1-2 tabs) SL/PO tid-qid, ac hs 1 SR cap ql2h Caution [C, +] T Effects w/ amantadine, antihistamines, antimuscarinics, haloperidol, phenothiazines, TCA, MAOI Contra BOO, GI obst, NAG, MyG, paralytic ileus, ulcerative colitis, MI Disp Caps, tabs SE Dry skin, xerostomia, constipation, anticholinergic SE, heat prostration w/ hot weather Interactions T Effects W/ amantadine, antimuscarinics, haloperidol, phenothiazines,... 

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