Amanita phaUoides

Plasma exchange is helpful in the removal of large molecular weight substances and highly protein-bound intoxicants. Toxic ingestions of poisonous mushrooms (e.g. amanita phaUoides [38, 39]) and snake-bite en-venomations [40] have been effectively treated with... 

Antamanide (AA), anti-amanita peptide , cyclo-(-Val-Pro-Pro-Ala-Phe-Phe-Pro-Pro-Phe-Phe °-), a non-toxic cyclic 10-peptide from Amanita phaUoides. Antamanide was isolated from the lipophilic part of extracts of A. phaUoides by chromatographic procedures, stmcturaUy characterized, and synthesized by Th. Wieland and co-workers in 1968. Administration at... 

Phalloidin is one of the poisons of the mushroom Amanita phaUoides with great toxicity. Only 50 pg are lethal for a mouse. Seven different amino acids are involved in its structure including such unusual hydroxy amino acids as hydroxy-leucine and allothreonine (T. Wieland). There is a bridge between tryptophan and the SH group of cysteine which yields hydroxy tryptophan upon hydrolysis. The formula is not reproduced here. 

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