Allylation of imines and related compounds

Grieco and Bahsas reported that iminium salts generated in situ from primary amines and formaldehyde can be allylated with preformed aUylstannane under aqueous conditions. Katritzky et al. foimd that the bismuth(lll)/aluminum system also mediated the aUylation of iminium cations to give amines. In this case, even methylation with iodomethane 

Allylation of acyloyl-imidazoles and pyrazoles with allyl hahde mediated by indium in aqueous media provides a facile regioselective synthesis of -imsaturated ketones. The re- 

Allylation reactions of electron-deficient imines with allyhc alcohol derivatives were effective in the presence of a catalytic amoimt of paUadium(O) complex and indium(I) 

Indium-mediated allylation reactions of a-keto imides derived from Oppolzer s sultam proceeded in aqueous THE in good yields and excellent diastereoselectivity. The indium-mediated allylation of the Oppolzer camphorsultam derivatives of glyoxylic oxime ether proceeded with excellent diastereoselectivity in aqueous media, providing a variety of enan-tiomerically pure a-amino acids. 

4 Propargylation/allenylation of carbonyls, imines, and related compounds 

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