Allyl quinolonyl ether

In the host-guest complex of template 60 with substrate 61, the two enantio-faces of quinolone 61 are distinctly discriminated. As one of the enantiofaces of 61 is blocked by the benzotriazole moiety of 60, photochemical attack to the substrate is expected to occur from the open face. Indeed, in the presence of 60 and its enantiomer (ent-60), highly enantioselective intramolecular [2 + 2] photocycloaddition of allyl quinolonyl ether 62 [134] and intermolecular [2 + 2] photocycloaddition of quinolone 61 to alkenes 63 [135] were reported to occur in solution (Scheme 23). The intermolecular photocyeloaddition of 63 to 61, as well as the intramolecular photocyeloaddition of 62 proceeded with excellent enantioselectivities (81-98% ee) and in high yields (61-89%). 

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See also in sourсe #XX -- [ ]

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