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Allergic disease inhibition mouse models

The first illustration of the potential of 35-kDa protein as a therapeutic inhibitor of inflammatory disease in vivo was produced using a guinea pig skin inflammation model. Purified recombinant vCKBP completely inhibited local eosinophil infiltration induced by eotaxin, a feature of allergic inflammatory reactions [16]. Similarly, the related vCKBP from orf vims has been recently shown to inhibit migration of monocytes in a mouse acute skin inflammation model induced by LPS [23]. [Pg.361]


See other pages where Allergic disease inhibition mouse models is mentioned: [Pg.151]    [Pg.33]    [Pg.151]    [Pg.152]    [Pg.155]    [Pg.2330]    [Pg.144]    [Pg.364]    [Pg.269]    [Pg.100]    [Pg.57]    [Pg.167]    [Pg.349]   
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