Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Alkyne derivatives alkoxycarbonylation

As is to be expected, an alkynic ketone undergoes a Michael addition with a carbanion, leading eventually to a pyranone (50JA1022). Using malonic esters, a 3-alkoxycarbonyl derivative results, which is hydrolyzed to the 2-oxopyran-3-carboxylic acid under alkaline conditions, but to the pyranone by sulfuric acid. Rapid ester exchange is observed with the initial products, the alcohol used as solvent determining the nature of the alkyl group in the 3-carboxylic esters (Scheme 90). [Pg.791]


See other pages where Alkyne derivatives alkoxycarbonylation is mentioned: [Pg.496]    [Pg.206]    [Pg.207]    [Pg.1089]    [Pg.80]    [Pg.561]    [Pg.264]    [Pg.281]    [Pg.282]    [Pg.253]    [Pg.387]   


SEARCH



Alkoxycarbonyl

Alkoxycarbonylation

Alkynes : derivatives

© 2024 chempedia.info