Alkaloidal desorption from matrix

Effect of Modifiers on Desorption of Alkaloidal Salts from Matrix 426... 

This chapter documents enhancements of the efficiency of SFE extraction of alkaloids from plant matrices using basified modifiers. Hence (1) The pure compound solubility of some free bases in pure supercritical C02 has been measured by investigating the effects of temperature, pressure or density of C02 (2) The solubilities of the alkaloidal salts were compared with those of their free bases in order to evaluate the difference of their solubilities influenced by a changing from free bases to salts (3) Polar solvents such as methanol and water, as initial modifiers, were used for the enhancement of the solubilities (4) The solubilities of the salts by non-basified modifiers such as neat methanol or water were compared with those of methanol or water basified with diethylamine (5) The effect of modifiers employed on the desorption of the compounds from a matrix were measured and compared with each other (5) On the basis of the results of pure compound extractability, SFE was performed on alkaloids from the plant... 

---