Aldoses chemical shifts

The H and NMR chemical shifts of the aldose reductase inhibitor 4(A)-2,3-dihydro-6-fluoro-2(R)-methylspiro-[chroman-4,4 -imidazoline]-2, 5 -dione (methylsorbinil, 66, Figure 17) and its seven synthetic intermediates have been completely assigned on the basis of DEPT, COSY, g-HSQC and g-HMBC. All the/-values for C-F (1 bonds), H-F (1 bonds), and H-H (3 bonds) have been determined <2005MRC1008>. 

M. J. King-Morris and A. S. Serianni, 13C NMR studies of [l-13C]aldoses Empirical rules correlating pyranose ring configuration and conformation with 13C chemical shifts and 13C-13C spin couplings, J. Am. Chem. Soc., 109 (1987) 3501-3508. 

---