Aldose to Ketose Conversion Utilizing the Osones

A method of considerable historical interest is the transformation of the aldoses to the ketoses through the osazohes and osones (247). In his classical work which led to the synthesis of the isomeric sugars, Fischer utilized this procedure. Although better preparative methods are now available, the method still is important for demonstrating structural relationships. The 

The Amadori rearrangement of aldosyl amines to aminodeoxyketoses (Chapter VIII), which is an intermediate reaction during osazone formation, also provides a means of passing from aldose to ketose structures. 

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