Aldehydes scandium trifluoromethanesulfonate

Alternatively, the authors have evaluated the polymer-bound scandium(III) bis (trifluoromethanesulfonate) as catalyst, and it proved to be slightly more active than the previous one. In a series of runs, the authors have re-evaluated the method and produced a library of 50 a-aminonitriles starting fi om ahphatic and aromatic aldehydes. In all runs, the reported yields were >99.6%. 

Kitazume and Zulfiqar have investigated the aza-Diels-Alder reaction in 1,8-diazabicyclo[5,4,0]-7-undecenium trifluoromethanesulfonate [EtDBU][OTf] [184] (Fig. 5.2-5). This reaction involved the scandium(iii) trifluoromethanesulfonate catalyzed reaction of an imine (usually generated in situ from an aldehyde and an amine) with a diene. An example of this reaction is given in Scheme 5.2-74. The yields in this reaction were high (80-99%) and it was found that the ionic liquid could be recycled and reused. 

---