Alcohols intramolecular bonding

Intramolecular H bond Polyvalent alcohols Chelation 3600-3500 (s) 3200-2500 Sharper than dimeric band above Broad and occasionally weak the lower the frequency, the stronger the intramolecular bond... 

The strength of the hydrogen bond in the enol is 1.7 times the hydrogen bond strength of the alcohol (3.2 vs. 1.9 kcal/mol). This is probably due to the better planar five-membered ring geometry for intramolecular bonding that can be attained in the enol. The OH - F bond... 

Cyclic 1,2-amino alcohols Intramolecular reductive coupling of carbonyl-tethered oxime ethers with Smij forms the cyclic products even in the absence of HMPA. Only one diastereomer is produced. After water has been added (20-25 equiv), the N-0 bond is cleaved in a subsequent reduction with the excess reagent at room temperature. A previous report indicates the failure of the intermolecular version. 

Reaction of 16-Electron Ruthenium and Iridium Amide Complexes with Acidic Alcohols Intramolecular C-H Bond Activation and the Isolation of Cyclometalated Complexes... 

The intensities of free OH stretching absorptions obey Beer s Law, and the extinction coefficients are similar for any single class of related materials, such as, for example, phenols [51]. The OH intensities of normal alcohols are also reasonably constant, so that substitution at the 2 or 3 carbon atom has no effect unless an intramolecular bond becomes possible. The intensities are all considerably lower than those of the phenols [124,145]. The intensities of the phenols can be related to the Hammett a values and are therefore connected with the OH polarity [154,155]. 

Koike, T. Ikariya, T. Reaction of 16-electron ruthenium and iridium amide complexes with acidic alcohols Intramolecular C-H bond activation and the isolation of cyclometalated complexes. Organometallics 2005, 24, 724-730. 

In all previous exarrples, the next step involved a molecule of solvent—either water or alcohol— which provided a nucleophilic oxygen atom to add to one carbon of the mercuiinium ion and open the ring. In this case, however, we can see that an oxygen atom already present in the substrate (at C7) becomes attached to one of the original double-bond carbons (C2) in the product. This process is one of intramolecular bond formation. After removal of the mercury by NaBH4, we arrive at the final product ... 

Tertiary Bonds These are weak intramolecular bonds (those between a polymer and itself) between repeat units that are widely separated in the one-dimensional structure (i.e., perhaps an alcohol in the side group of the third repeat unit hydrogen bonds to a carboxylic acid in the 8000th repeat unit). These bonds hold the three-dimensional structure of an individual polymer in place. 

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