Alcohols chiral palladacycles

Sigmatropic Rearrangement of Trichloroacetimidates The development of the asymmetric palladium(II)-catalyzed [3,3]-sigmatropic rearrangement of trichloroacetimidates has proven to be a powerful method for the generation of chiral amines from achiral allylic alcohols [12]. In particular, the cobalt oxazoline palladacycles, such as COP-Cl (4), have been shown to be particularly efficient for this transformation (Scheme 5.1) [13]. 

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