Albuterol applications

Although very efficient, the broad application of the direct preparation is restricted due to the limited number of pure starting enantiomers. The design of a multistep process that includes asymmetric synthesis is cumbersome and the development costs may be quite high. This approach is likely best suited for the multi-ton scale production of commodity enantiomers such as the drugs ibuprofen, naproxen, atenolol, and albuterol. However, even the best asymmetric syntheses do not lead to products in an enantiomerically pure state (100 % enantiomeric excess). Typically, the product is enriched to a certain degree with one enantiomer. Therefore, an additional purification step may be needed to achieve the required enantiopurity. 

Applications of p-Agonists. Most of the j3-selective adrenergic agonists, albuterol (13 salbutamol in Europe), bitolterol (14),... 

A Adam, et al. Radioimmunoassay for albuterol using a monoclonal antibody— Application for direct quantification in horse urine. J Immunoassay 11 329, 1990. 

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