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Alanyl-PNA

Figure 5-8 Structure of DNA, PNA, OPNA, and alanyl-PNA. In alanyl-PNA, the peptide strand is represented with the absolute chirality alternating at each residue along the strand. B designates a nucleobase in all structures. Figure 5-8 Structure of DNA, PNA, OPNA, and alanyl-PNA. In alanyl-PNA, the peptide strand is represented with the absolute chirality alternating at each residue along the strand. B designates a nucleobase in all structures.
Two adjacent pairs of histidines have been introduced in alanyl, alanyl/ homoalanyl, homoalanyl, and alanyl/norvalyl PNA duplexes, which have a duplex width of 14, 15, 16.5, and 18 A, respectively (141). A hypothesis was set forth, but not proven, that the four histidines coordinate one metal ion in the narrower duplexes and a dimer of metal ions bridged by water ligands in... [Pg.588]

See other pages where Alanyl-PNA is mentioned: [Pg.177]    [Pg.178]    [Pg.174]    [Pg.175]    [Pg.554]    [Pg.143]    [Pg.144]    [Pg.177]    [Pg.178]    [Pg.174]    [Pg.175]    [Pg.554]    [Pg.143]    [Pg.144]    [Pg.88]    [Pg.200]    [Pg.282]    [Pg.105]   
See also in sourсe #XX -- [ Pg.143 ]



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