AIDS immunoglobulin preparations

AIDS-immunoglobulins are also known as HTV-immunoglobulins. More recently, AIDS immunoglobulin preparations containing HlV-neutarlizing antibodies have been prepared from the plasma of asymptomatic HfV-positive subject. They are being tried for passive immunization in patients with AIDS or AIDS-related complex (ARC). 

Schechter, I. (1973). Biologically and chemically pure mRNA coding for a mouse immunoglobulin L-chain prepared with the aid of antibodies and immobilized oligothymidine. Proc. Natl. Acad. Sci. USA 70, 2256-2260. 

E. Reconstitute the lyophilized material with 10 mL of the diluent supplied, gently swirling for 10-30 minutes. Avoid shaking the preparation because this may destroy the immunoglobulins (indicated by the formation of foam). Dilution with 50-200 mL of saline may aid solubilization. 

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