Aggressive symptoms

D/C all antiretrovirals as well as any other possible cause aggressive symptom support do not rechallenge patient with offending agent if caused by NVP, avoid NNRTI class, if possible... 

Finally, consistent with the impression that novel antipsychotics may have mood-regulating properties in adults, a recent retrospective chart review found risperidone helpful for manic and aggressive symptoms in 28 juvenile manic patients (208). 

FIGURE 10-5. Aggressive symptoms and hostility are associated with several conditions in addition to schizophrenia, including bipolar disorder, attention deficit hyperactivity disorder (ADHD) and conduct disorder (conduct dis.), childhood psychosis, Alzheimer s and other dementias, and borderline personality disorder, among others. 

Although aggressive symptoms are common in schizophrenia, they are far from unique to this condition. Thus, these same symptoms are frequently associated with bipolar disorder, childhood psychosis, borderline personality disorder, drug abuse, Alzheimer and other dementias, attention deficit hyperactivity disorder, conduct disorders in children, and many others (Fig. 10—5). 

FIGURE 11-56. Aggressive symptom pharmacy. Atypical antipsychotics (SDA), when sufficiently effective, are preferable (first line) to conventional antipsychotics (D2) for the management of aggression, hostility, and impulse control because of their more favorable side effect profiles. However, in an acute situation, intramuscular conventional antipsychotics or benzodiazepines (BZ) may be useful, and conventional antipsychotics or clozapine (C) may be required when atypical antipsychotics are not effective (second-line). 

Anticonvulsants have sedative side effects and therefore drugs such as carbamazepine have occasionally been used to treat conduct disorders. There is no evidence that such drugs are useful in the control of aggressive symptoms. 

Cognitive symptoms Unstable mood Aggressive symptoms... 

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