Agarose-acrylamide

Various support media may be employed in electrophoretic techniques. Separation on agarose, acrylamide, and paper is influenced not only by electrophoretic mobiUty, but also by sieving of the samples through the polymer mesh. The finer the weave of selected matrix, the slower a molecule travels. Therefore, molecular weight or molecular length, as well as charge, can influence the rate of migration. 

A. C. Peacock and C. W. Dingman, Biochemistry, 7 688-674 (1968). Molecular Weight Estimation and Separation of Ribonucleic Acid by Electrophoresis in Agarose-Acrylamide Composite Gels. 

Electrophoresis agarose/acrylamide gelsprotein separations isolation of specific DNA restriction fragments first DNA sequencing analysis of transcription products (Northern blotting) or proteins (+Western blotting)... 

Using an agarose-acrylamide copolymer product also reduced, as shown in Scheme 3b " presumed to be this derivative. 

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