Diabetes, adrenocorticotropic hormone

In other situations, stress factors such as emotional disturbances, fasting, starvation, or diabetes, are signals to the pituitary gland to release adrenocorticotropic hormone (ACTH), which acts both alone on tissues and stimulates secretion of other stress hormones by the adrenal glands. The net effects of these stress-responsive hormones are the tearing down (catabolism) of fat, muscle, and/or bone tissues, so as to provide essential nutrients for metabolism. 

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