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Adrenocorticoid biosynthesis

Alclometasone is a topical glucocorticoid with antiinflammatory, antipruritic, and vasoconstrictive properties. It acts by inducing phospholipase A2 inhibitory proteins, thus controlling biosynthesis of potent mediators of inflammation. Alclometasone (0.05% ointment) is a topical adrenocorticoid with antiinflammatory properties that is indicated in inflammation of corticosteroid-responsive dermatoses. [Pg.52]

Fig. 44.22. Biosynthesis of the adrenocorticoids from cholesterol. The enzymes involved are (a) side chain cleavage, b) 17a-hydroxylase, (c) 5-ene-3p-hydroxy-steroid dehydrogenase, (cf) 3-oxosteroid-4,5-isomerase, (e) 21-hydroxylase, (f) 11 p-hydroxylase, and (g)... Fig. 44.22. Biosynthesis of the adrenocorticoids from cholesterol. The enzymes involved are (a) side chain cleavage, b) 17a-hydroxylase, (c) 5-ene-3p-hydroxy-steroid dehydrogenase, (cf) 3-oxosteroid-4,5-isomerase, (e) 21-hydroxylase, (f) 11 p-hydroxylase, and (g)...
See other pages where Adrenocorticoid biosynthesis is mentioned: [Pg.275]    [Pg.288]    [Pg.2028]    [Pg.1345]    [Pg.275]    [Pg.288]    [Pg.2028]    [Pg.1345]    [Pg.1179]    [Pg.1305]    [Pg.1314]    [Pg.1316]    [Pg.1345]   
See also in sourсe #XX -- [ Pg.883 , Pg.885 , Pg.1304 ]



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Adrenocorticoids

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